let's talk about genetics for a minute
May. 2nd, 2005 01:55 amin what must have been the mid- to late-1930's, my grandmother's older sister died of (i believe) leukemia. she was about 16.
in the early- to mid-1940's, my grandmother's older brother died of -- i'm not sure what. something heart-related, perhaps. he was about 20.
in the late 1970's, my grandmother's parents died within a short interval of each other; i don't know the causes or their ages off the top of my head, but i think they were both in their mid- to late-70's.
in about 1991, my uncle had surgery for colon cancer, which seems to have been entirely successful, kineahora -- he is now 55.
in 1994, my grandmother (who had a history of throat cancer, i think) developed leukemia, had chemo and radiation, and caught pneumonia with no white blood cells to fight it. she was almost 70.
in 1995, my grandfather died of liver cancer. he was 71.
over the years, my grandfather's older sister has lost two of her sons. i don't know the causes -- i think one was heart-related and one was cancer-related, but i'm not sure. they were both in their 50's.
in 2003, my aunt was diagnosed with cancer in the ovaries and pancreas, which i think they worked out originated in the colon. she was dead three weeks later; she was 58.
three weeks ago, my grandmother's younger sister was diagnosed with pancreatic cancer. she died today; she was about 75.
so, first off, i know they've identified a gene that flags you as Incredibly Susceptible To Colon Cancer. post-surgery, my uncle had the test and discovered that he had the gene, and my aunt and my father both also had the test -- i don't know what her result was, but my father's was that he doesn't have it, which means he can't have given it to me.
secondly, on my mother's side of the family the general habit is to live to be about six trillion years old and shrivel up like a raisin.
but, taking the first and second items together: i'm just put together more like my father's side of the family -- specifically, like his mother's side of his side of the family. that's most of how i'm built on the outside (apart from a couple of cosmetic features like the straightness of my hair and the cleft in my chin); doesn't it make sense that i'm likely to be more like them on the inside as well? put another way, many of the people listed above made efforts to take care of themselves and live healthy lives and all that, and they got cancer and died young just the same. what, you know, are my odds?
(thirdly, my grandmother's younger brother is the last man standing, now. he's 70. i can't go to the funeral, but i wish i could, because out of everyone, he's the one i want most to give a big hug.)
in the early- to mid-1940's, my grandmother's older brother died of -- i'm not sure what. something heart-related, perhaps. he was about 20.
in the late 1970's, my grandmother's parents died within a short interval of each other; i don't know the causes or their ages off the top of my head, but i think they were both in their mid- to late-70's.
in about 1991, my uncle had surgery for colon cancer, which seems to have been entirely successful, kineahora -- he is now 55.
in 1994, my grandmother (who had a history of throat cancer, i think) developed leukemia, had chemo and radiation, and caught pneumonia with no white blood cells to fight it. she was almost 70.
in 1995, my grandfather died of liver cancer. he was 71.
over the years, my grandfather's older sister has lost two of her sons. i don't know the causes -- i think one was heart-related and one was cancer-related, but i'm not sure. they were both in their 50's.
in 2003, my aunt was diagnosed with cancer in the ovaries and pancreas, which i think they worked out originated in the colon. she was dead three weeks later; she was 58.
three weeks ago, my grandmother's younger sister was diagnosed with pancreatic cancer. she died today; she was about 75.
so, first off, i know they've identified a gene that flags you as Incredibly Susceptible To Colon Cancer. post-surgery, my uncle had the test and discovered that he had the gene, and my aunt and my father both also had the test -- i don't know what her result was, but my father's was that he doesn't have it, which means he can't have given it to me.
secondly, on my mother's side of the family the general habit is to live to be about six trillion years old and shrivel up like a raisin.
but, taking the first and second items together: i'm just put together more like my father's side of the family -- specifically, like his mother's side of his side of the family. that's most of how i'm built on the outside (apart from a couple of cosmetic features like the straightness of my hair and the cleft in my chin); doesn't it make sense that i'm likely to be more like them on the inside as well? put another way, many of the people listed above made efforts to take care of themselves and live healthy lives and all that, and they got cancer and died young just the same. what, you know, are my odds?
(thirdly, my grandmother's younger brother is the last man standing, now. he's 70. i can't go to the funeral, but i wish i could, because out of everyone, he's the one i want most to give a big hug.)